turbid and they were compelled to share their environment with foreign entities together with policies that were far from nature’s law. the indigenous people of Australia embarked on a platform different from their natural environment. Such change on one hand provided them with an improved health care system and on the other introduced them with different diseases previously unknown to them. The change in types of disease exposure for the indigenous people of Australia after they realized similar exposure and were subject to government policies are worthy of consideration and is expected to result in an understanding of their present health status. Furthermore, it is also interesting to find out that how these historical and political factors have impacted the Social Determinants of Health (SDoH) and thereby influenced the health status of the contemporary Australian indigenous people (Australian Human Rights Commission, 2007). The present paper tries to analyze these aspects to conclude the same.It is widely believed that the indigenous people of Australia were in far better health than the contemporary European people back in 1788. Unlike the European people smallpox, measles, influenza, tuberculosis, scarlet fever, venereal syphilis and gonorrhea were absent among them. They usually suffered from hepatitis B, common bacterial infections, and some intestinal parasites. Most of the deaths among indigenous people were from trauma and cases of anemia, arthritis, periodontal disease, tooth problem were common among them. However, as a whole the disease exposure and its subsequent impact on the Australian indigenous population were far lower among the indigenous Australian people than that of the European population of the 18th century. However all these have changed once the European settlers made their way into the Australian inland. Diseases previously unknown to Indigenous Australian people started to take its toll from them and smallpox resulted in huge loss of lives. Not only these diseases impacted the immediate sufferer rather they also initiated severe social disruption and epidemic that depopulated the Australian indigenous people.